Rey Mysterio suffered an apparent bicep injury at last night's SmackDown/ECW brand house show in Santiago, Chile. He flew back to the U.S. to meet with Dr. James Andrews, however hasn't had an MRI done. According to Dave Meltzer, he does not want to miss Wrestlemania if it's at all possible. We will know more after he sees Andrews and they determine the severity of the injury. Surgery would put him out around six months.

Mysterio is scheduled to wrestle Edge for the WWE World Heavyweight Championship this Sunday at No Way Out.

Here is WWE.com's statement regarding Mysterio's sudden injury:

Rey Mysterio injured during South American tour

Rey Mysterio’s quest to regain the World Championship may have suffered a severe setback in Santiago, Chile, on Wednesday night.

The injury occurred during Wednesday’s live event at Arena Santiago, where Mysterio teamed with Kane against Zack Ryder & Curt Hawkins. During the tag contest, Rey suffered an apparent injury to his right arm – specifically his bicep. Clearly in pain, the Master of the 619 gutted it out and finished the match, then was quickly examined by WWE athletic trainer Jason Crivello upon leaving the ring.

Mysterio flew back to the United States late Wednesday night, and is currently in Gulf Breeze, Fla., waiting to meet with world-renowned surgeon Dr. James Andrews, who will determine the extent of the injury. Regardless of Dr. Andrews’ findings, Mysterio has his heart set on competing this Sunday night at No Way Out, where he is scheduled to face Edge for the World Championship.

Stay with WWE.com as more updates become available regarding Mysterio’s condition.